What medicine should I take to get gastric ulcer? Revealing the relationship between common drugs and gastric mucosal damage
Gastric ulcer is a common digestive system disease, and its occurrence is closely related to drug use. In recent years, with the widespread use of nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics and other drugs, the incidence of drug-induced gastric ulcer has increased significantly. This article combines hot topics and medical research on the Internet in the past 10 days to analyze which drugs may cause gastric ulcers and provide structured data reference.
1. Common drugs that can easily cause gastric ulcers
| drug class | Representative medicine | ulcerogenic mechanism | risk level |
|---|---|---|---|
| Nonsteroidal anti-inflammatory drugs (NSAIDs) | Aspirin, ibuprofen, naproxen | Inhibit prostaglandin synthesis and weaken gastric mucosal protection | high |
| Glucocorticoids | Prednisone, dexamethasone | Increase gastric acid secretion and reduce mucus secretion | Middle to high |
| antibiotics | Clarithromycin, doxycycline | Destroy the balance of intestinal flora and indirectly damage the gastric mucosa | in |
| antiplatelet drugs | clopidogrel | Interference with gastric mucosal repair | in |
| antineoplastic drugs | 5-Fluorouracil | direct cytotoxic effects | high |
2. Typical symptoms of drug-induced gastric ulcer
If the following symptoms occur after long-term use of the above drugs, you need to be alert to gastric ulcers:
3. How to reduce the risk of drug-induced gastric ulcer?
| Precautions | Specific methods |
|---|---|
| Rational use of medication | Avoid combining NSAIDs with glucocorticoids and prefer enteric-coated tablets |
| joint protectant | Long-term use of NSAIDs with proton pump inhibitors (such as omeprazole) |
| Monitoring and inspection | High-risk groups should undergo regular gastroscopy |
| lifestyle adjustments | Avoid alcohol and spicy food irritation |
4. Recent hot cases and discussions
1.An Internet celebrity suffered a gastric perforation due to long-term use of painkillers: Social platforms are hotly discussing the risks of abusing ibuprofen, and doctors remind the daily dose not to exceed 1,200mg.
2.Study on the synergistic damage caused by Helicobacter pylori and drugs: Latest data show that people with Helicobacter pylori infection have a three-fold increased risk of drug-induced ulcers.
3.Controversy over gastric ulcer caused by traditional Chinese medicine: Some traditional Chinese medicines containing strong acidic ingredients (such as Evodia) have been included in the monitoring list.
Summary: Drug-induced gastric ulcer can be prevented and controlled. The key lies in scientific medication and early intervention. If you need to take high-risk drugs for a long time, it is recommended to formulate a personalized protection plan under the guidance of a doctor.
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